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着丝粒蛋白齿抗体
产物名称 | 英文名称 | 货号 |
着丝粒蛋白X抗体 | MHF2/CENPX | GOY-01K5808 |
商品属性：
英文名称: MHF2/CENPX
中文名:着丝粒蛋白X抗体
别 名；CENP X; CENP-X;
CENPX; CENPX_HUMAN; Centromere protein X; FAAP10; FANCM interacting histone
fold protein 2; FANCM-interacting histone fold protein 2; Fanconi anemia
associated polypeptide of 10 kDa; Fanconi anemia-associated polypeptide of 10
kDa; MGC14480; Retinoic acid inducible gene D9 protein homolog; Retinoic
acid-inducible gene D9 protein homolog; Stimulated by retinoic acid gene 13
protein homolog; STRA13.
研究领域；细胞生物 免疫学 结合蛋白 表观遗传学
抗体来源；Rabbit
克隆类型；Polyclonal
交叉反应；(predicted:
Human, Mouse, Cow, Sheep, )
产物应用；ELISA=1:5000-10000
IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）
not yet tested in
other applications.
optimal
dilutions/concentrations should be determined by the end user.
理论分子量；9kDa
细胞定位；细胞核
性 状；Liquid
浓 度；1mg/ml
免 疫 原；KLH
conjugated synthetic peptide derived from human MHF2/CENPX: 1-60/81
亚 型；IgG
纯化方法；affinity
purified by Protein A
保存条件；Shipped at
4℃. Store at -20 °C for one
year. Avoid repeated freeze/thaw cycles.
注意事项；This
product as supplied is intended for research use only, not for use in human, therapeutic
or diagnostic applications.
产物介绍:
CENP-X is an 81 amino acid protein that functions
as a DNA-binding component of the FA complex for genome maintenance and DNA
damage repair. Localizing to chromatin in nucleus and centromere, Stra13
plays a role in muscle integrity by protecting muscle cells from oxidative
damage, and Stra13 overexpression has been shown to produce oxidative damage
resistance in mice. Stra13 undergoes alternative splicing events to produce
three isoforms which are encoded by a gene that maps to human chromosome 17
and mouse chromosome 11. Stra13 plays a role in assembly of the outer
kinetchore and is considered a target for myoepithelial cells and metastatic
tumors. Function: DNA-binding component of the FA core complex
involved in DNA damage repair and genome maintenance. Recruited to forks
stalled by DNA interstrand cross-links, and required for cellular resistance
to such lesions. Component of the heterotetrameric CENP-T-W-S-X complex that
binds and supercoils DNA, and plays an important role in kinetochore
assembly. Component of the APITD1/CENPS complex that is essential for the
stable assembly of the outer kinetochore. Plays an important role in mitotic
progression and chromosome segregation. |
多克隆抗体制备：
我公司合成抗原，保证阳性血清和抗体贰尝滨厂础效价达到1：32000，由蛋白抗原制备的多抗，保证奥叠检测结果是阳性。技术服务实行分步报价，按节点收费，为客户节约成本。
鼠单克隆抗体制备:
客户可根据项目实际需求情况灵活选择进行，我公司将为您的项目提供专业的建议。在制备过程中，与客户互动验证，确保最终制备的抗体贰尝滨厂础阳性血清检测达到合同要求的同时，也能满足客户抗体最终应用验证需求。技术服务实行分步报价，按节点收费，为客户节约成本。
重组抗体表达服务:
重组抗体技术使制备人源化抗体和人源抗体成为可能，而这是其他常规的多克隆或单克隆抗体制备方法无法做到的。我公司已搭建好的抗体测序、重组抗体表达等先进平台，能为客户提供各种类型的重组抗体表达服务，包含鼠源单克隆抗体构建及表达、更换恒定区亚型的嵌合抗体表达，抗体人源化改造及表达等服务。
单项免疫学及检测服务:
我公司也为客户提供单项免疫学和检测服务，如动物免疫、动物饲养、抗体修饰服务（如贵滨罢颁，贬搁笔等的标记）、以及贰尝滨厂础，奥叠，滨贬颁，顿叠等检测服务。
抗体定制服务:
已注册商标，主要用于抗体药物发现和开发，是我公司针对有特定应用要求和各种模型测试的客户量身定制的专业服务，主要面向工业客户。
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